A research paper published in a recent issue of Nature Communications (https://www.nature.com/articles/s41467-019-09900-9) describes the results of a study conducted to investigate how treatment of a neglected tropical disease called "schistosomiasis" affects the immunology of African women, in particular with regard to HIV susceptibility.

The article's first author, Dr. Sergey Yegorov, currently assistant professor at Suleyman Demirel University, says: "I am thankful for the opportunity to be part of an international effort striving to prevent common viral and parasitic infections in low- and middle-income countries, especially in Africa. A number of diseases exert a heavy toll on people’s lives in an East African country Uganda: HIV affects approximately one out of 15 adults; schistosomiasis is a neglected tropical disease and is rarely diagnosed despite a prevalence of over 60% in some communities. Our clinical trial of schistosomiasis treatment in Ugandan women demonstrated a substantial reduction of HIV susceptibility after anthelminthic therapy. These research findings are very exciting because they suggest that fighting curable but neglected diseases could help curb the spread of other debilitating infections, such as HIV, in Africa and around the globe."

This research was supported by Canadian Institutes of Health Research and a Vanier Canada Graduate Scholarship. Dr. Sergey Yegorov is also thankful to SDU for the support he received during the final stages of the manuscript preparation and for the University's commitment to develop a research program that will facilitate biomedical research in Kazakhstan.

More about this research in English and Russian: https://tspace.library.utoronto.ca/handle/1807/92143